Xydalba: bactericidal mechanism of action

Disruption of cell wall synthesis means that Xydalba is bactericidal4

Diagram showing the disruption of cell wall synthesis meaning that Xydalba is bactericidal

Mechanism of action1,4

Diagram explaining the mechanism of action
Ala, alanine; Glu, glutamate; Gly, glycine; Lys, lysine; NAG, N-acetylglucosamine; NAM, N-acetylmuramic acid.

Xydalba interrupts cell wall synthesis by binding to the terminal D-alanyl-D-alanine of the stem peptide in nascent cell wall peptidoglycan, preventing cross-linking of disaccharide subunits resulting in bacterial cell death.1

Xydalba SmPC
4 Pommerville JC. Alcamo’s Fundamentals of Microbiology. Sudbury, MA: Jones and Bartlet Publishers, LLC; 2014:99-132